UI: T020
STY: Acquired Abnormality
ABR: acab
STN: A1.2.2.2
DEF: An abnormal structure, or one that is abnormal in size or location, found
in or deriving from a previously normal structure.  Acquired abnormalities are
distinguished from diseases even though they may result in pathological
functioning (e.g., "hernias incarcerate").
HL: {isa} Anatomical Abnormality

UI: T052
STY: Activity
ABR: acty
STN: B1
DEF: An operation or series of operations that an organism or machine carries
out or participates in.
UN: Few concepts will be assigned to this broad type.  Wherever possible, one of
the more specific types from this hierarchy will be chosen.  For concepts
assigned to this type, the focus of interest is on the activity.  When the focus
of interest is the individual or group that is carrying out the activity, then a
type from the 'Behavior' hierarchy will be chosen.  In general, concepts will not
receive a type from both the 'Activity' and the 'Behavior' hierarchies.
HL: {isa} Event;
{inverse_isa} Behavior;
{inverse_isa} Daily or Recreational Activity;
{inverse_isa} Occupational Activity;
{inverse_isa} Machine Activity

UI: T100
STY: Age Group
ABR: aggp
STN: A2.9.4
DEF: An individual or individuals classified according to their age.
HL: {isa} Group

UI: T087
STY: Amino Acid Sequence
ABR: amas
STN: A2.1.5.3.2
DEF: The sequence of amino acids as arrayed in chains, sheets, etc., within the
protein molecule.  It is of fundamental importance in determining protein
structure.
HL: {isa} Molecular Sequence

UI: T116
STY: Amino Acid, Peptide, or Protein
ABR: aapp
STN: A1.4.1.2.1.7
DEF: Amino acids and chains of amino acids connected by peptide linkages.
UN: When the concept is both an enzyme and a protein, this type and the type
'Enzyme' will be assigned.
HL: {isa} Organic Chemical

UI: T011
STY: Amphibian
ABR: amph
STN: A1.1.3.1.1.1
DEF: A cold-blooded, smooth-skinned vertebrate which characteristically hatches
as an aquatic larva, breathing by gills.  When mature, the amphibian breathes
with lungs.
HL: {isa} Vertebrate

UI: T190
STY: Anatomical Abnormality
ABR: anab
STN: A1.2.2
DEF: An abnormal structure, or one that is abnormal in size or location.
UN: Use this type if the abnormality in question can be either an acquired or
congenital abnormality.  Neoplasms are not included here.  These are given the
type 'Neoplastic Process'.  If an anatomical abnormality has a pathologic
manifestation, then it will additionally be given the type 'Disease or
Syndrome', e.g., "Diabetic Cataract" will be double-typed for this reason.
HL: {isa} Anatomical Structure;
{inverse_isa} Congenital Abnormality;
{inverse_isa} Acquired Abnormality

UI: T017
STY: Anatomical Structure
ABR: anst
STN: A1.2
DEF: A normal or pathological part of the anatomy or structural organization of
an organism.
UN: Few concepts will be assigned to this broad type.
NH: Y
HL: {isa} Physical Object;
{inverse_isa} Embryonic Structure;
{inverse_isa} Fully Formed Anatomical Structure;
{inverse_isa} Anatomical Abnormality

UI: T008
STY: Animal
ABR: anim
STN: A1.1.3.1
DEF: An organism with eukaryotic cells, and lacking stiff cell walls, plastids
and photosynthetic pigments.
HL: {isa} Eukaryote;
{inverse_isa} Vertebrate

UI: T195
STY: Antibiotic
ABR: antb
STN: A1.4.1.1.1.1
DEF: A pharmacologically active compound produced by growing microorganisms
which kill or inhibit growth of other microorganisms.
HL: {isa} Pharmacologic Substance

UI: T194
STY: Archaeon
ABR: arch
STN: A1.1.1
DEF: A member of one of the three domains of life, formerly called
Archaebacteria under the taxon Bacteria, but now considered separate and
distinct.  Archaea are characterized by: 1) the presence of characteristic tRNAs
and ribosomal RNAs; 2) the absence of peptidoglycan cell walls; 3) the presence
of ether-linked lipids built from branched-chain subunits; and 4) their
occurrence in unusual habitats.  While archaea resemble bacteria in morphology
and genomic organization, they resemble eukarya in their method of genomic
replication.
HL: {isa} Organism

UI: T007
STY: Bacterium
ABR: bact
STN: A1.1.2
DEF: A small, typically one-celled, prokaryotic micro-organism.
HL: {isa} Organism

UI: T053
STY: Behavior
ABR: bhvr
STN: B1.1
DEF: Any of the psycho-social activities of humans or animals that can be
observed directly by others or can be made systematically observable by the use
of special strategies.
UN: Few concepts will be assigned to this broad type.  For concepts assigned to
the 'Behavior' hierarchy, the focus of interest is on the individual or group
that is carrying out the activity.  When the activity is of paramount interest,
then a type from the 'Activity' hierarchy will be chosen.  In general, concepts
will not receive a type from both the 'Behavior' and the 'Activity' hierarchies.
NH: Y
HL: {isa} Activity;
{inverse_isa} Social Behavior;
{inverse_isa} Individual Behavior

UI: T038
STY: Biologic Function
ABR: biof
STN: B2.2.1
DEF: A state, activity or process of the body or one of its systems or parts.
UN: Few concepts will be assigned to this broad type.
NH: Y
HL: {isa} Natural Phenomenon or Process;
{inverse_isa} Physiologic Function;
{inverse_isa} Pathologic Function

UI: T123
STY: Biologically Active Substance
ABR: bacs
STN: A1.4.1.1.3
DEF: A generally endogenous substance produced or required by an organism, of
primary interest because of its role in the biologic functioning of the organism
that produces it.
UN: If a substance is both endogenous and typically used as a drug, then this
type and the type 'Pharmacologic Substance' are assigned.
HL: {isa} Chemical Viewed Functionally;
{inverse_isa} Neuroreactive Substance or Biogenic Amine;
{inverse_isa} Hormone;
{inverse_isa} Enzyme;
{inverse_isa} Vitamin;
{inverse_isa} Immunologic Factor;
{inverse_isa} Receptor

UI: T091
STY: Biomedical Occupation or Discipline
ABR: bmod
STN: A2.6.1
DEF: A vocation, academic discipline, or field of study related to biomedicine.
Emergency Nursing
HL: {isa} Occupation or Discipline

UI: T122
STY: Biomedical or Dental Material
ABR: bodm
STN: A1.4.1.1.2
DEF: A substance used in biomedicine or dentistry predominantly for its
physical, as opposed to chemical, properties.  Included here are biocompatible
materials, tissue adhesives, bone cements, resins, toothpastes, etc.
HL: {isa} Chemical Viewed Functionally

UI: T012
STY: Bird
ABR: bird
STN: A1.1.3.1.1.2
DEF: A vertebrate having a constant body temperature and characterized by the
presence of feathers.
HL: {isa} Vertebrate

UI: T029
STY: Body Location or Region
ABR: blor
STN: A2.1.5.2
DEF: An area, subdivision, or region of the body demarcated for the purpose of
topographical description.
Structure of lateral surface of thumb; Lower anterior segment of dental arch
UN: When assigning this type, consider whether 'Body Part, Organ, or Organ
Component' might be the correct choice.
NH: Y
HL: {isa} Spatial Concept

UI: T023
STY: Body Part, Organ, or Organ Component
ABR: bpoc
STN: A1.2.3.1
DEF: A collection of cells and tissues which are localized to a specific area or
combine and carry out one or more specialized functions of an organism.  This
ranges from gross structures to small components of complex organs.  These
structures are relatively localized in comparison to tissues.
distal tibia
UN: When assigning this type, consider whether 'Body Location or Region' might
be the correct choice.
HL: {isa} Fully Formed Anatomical Structure

UI: T030
STY: Body Space or Junction
ABR: bsoj
STN: A2.1.5.1
DEF: An area enclosed or surrounded by body parts or organs or the place where
two anatomical structures meet or connect.
of Held's space
NH: Y
HL: {isa} Spatial Concept

UI: T031
STY: Body Substance
ABR: bdsu
STN: A1.4.2
DEF: Extracellular material, or mixtures of cells and extracellular material,
produced, excreted, or accreted by the body.  Included here are substances such
as saliva, dental enamel, sweat, and gastric acid.
procedure
NH: Y
HL: {isa} Substance

UI: T022
STY: Body System
ABR: bdsy
STN: A2.1.4.1
DEF: A complex of anatomical structures that performs a common function.
Skeletal system
HL: {isa} Functional Concept

UI: T118
STY: Carbohydrate
ABR: carb
STN: A1.4.1.2.1.8
DEF: A generic term that includes monosaccharides, oligosaccharides, and
polysaccharides as well as substances derived from monosaccharides by reduction
of the carbonyl group (alditols), by oxidation of one or more terminal group to
carboxylic acids, or by replacement of one or more hydroxy groups by a hydrogen
atom, an amino group, a thiol group or similar heteroatomic groups.  It also
includes derivatives of these compounds.  Included here are sugar phosphates.
Excluded are glycolipids and glycoproteins.
UN: Glycoproteins should only be typed as 'Amino Acid, Peptide, or Protein'.
Sugar phosphates should only be typed as 'Carbohydrate'.  Glycolipids should only
be typed as 'Lipid'.
HL: {isa} Organic Chemical

UI: T088
STY: Carbohydrate Sequence
ABR: crbs
STN: A2.1.5.3.3
DEF: The sequence of carbohydrates within polysaccharides, glycoproteins, and
glycolipids.
HL: {isa} Molecular Sequence

UI: T025
STY: Cell
ABR: cell
STN: A1.2.3.3
DEF: The fundamental structural and functional unit of living organisms.
HL: {isa} Fully Formed Anatomical Structure

UI: T026
STY: Cell Component
ABR: celc
STN: A1.2.3.4
DEF: A part of a cell or the intercellular matrix, generally visible by light
microscopy.
HL: {isa} Fully Formed Anatomical Structure

UI: T043
STY: Cell Function
ABR: celf
STN: B2.2.1.1.3
DEF: A physiologic function inherent to cells or cell components.
HL: {isa} Physiologic Function

UI: T049
STY: Cell or Molecular Dysfunction
ABR: comd
STN: B2.2.1.2.2
DEF: A pathologic function inherent to cells, parts of cells, or molecules.
UN: This is not intended to be a repository for diseases whose molecular basis
has been established.
HL: {isa} Pathologic Function

UI: T103
STY: Chemical
ABR: chem
STN: A1.4.1
DEF: Compounds or substances of definite molecular composition.  Chemicals are
viewed from two distinct perspectives in the network, functionally and
structurally.  Almost every chemical concept is assigned at least two types,
generally one from the structure hierarchy and at least one from the function
hierarchy.
UN: Few concepts will be assigned to this broad type.
HL: {isa} Substance;
{inverse_isa} Chemical Viewed Structurally;
{inverse_isa} Chemical Viewed Functionally

UI: T120
STY: Chemical Viewed Functionally
ABR: chvf
STN: A1.4.1.1
DEF: A chemical viewed from the perspective of its functional characteristics or
pharmacological activities.
UN: A specific chemical will not be assigned here.  Groupings of chemicals viewed
functionally, such as "Aerosol Propellants" may appropriately be assigned here.
A name that is inherently functional, such as "Food Additives", will not also be
assigned a type from the 'Chemical Viewed Structurally' hierarchy.
HL: {isa} Chemical;
{inverse_isa} Pharmacologic Substance;
{inverse_isa} Biomedical or Dental Material;
{inverse_isa} Biologically Active Substance;
{inverse_isa} Indicator, Reagent, or Diagnostic Aid;
{inverse_isa} Hazardous or Poisonous Substance

UI: T104
STY: Chemical Viewed Structurally
ABR: chvs
STN: A1.4.1.2
DEF: A chemical or chemicals viewed from the perspective of their structural
characteristics.  Included here are concepts which can mean either a salt, an
ion, or a compound (e.g., "Bromates" and "Bromides").
UN: Concepts are assigned to this type if they can be both organic and
inorganic, e.g.  sulfur compounds.  Do not use this type if the concept has an
important functional aspect, e.g., "Mylanta Double Strength Liquid" contains
Al(OH)3, Mg(OH)2, and simethicone, but would be assigned only to 'Pharmacologic
Substance'.
HL: {isa} Chemical;
{inverse_isa} Organic Chemical;
{inverse_isa} Element, Ion, or Isotope;
{inverse_isa} Inorganic Chemical

UI: T185
STY: Classification
ABR: clas
STN: A2.4.1
DEF: A term or system of terms denoting an arrangement by class or category.
HL: {isa} Intellectual Product

UI: T201
STY: Clinical Attribute
ABR: clna
STN: A2.3.1
DEF: An observable or measurable property or state of an organism of clinical
interest.
time:Serum/Plasma:Quantitative:Without P-5'-P; urine acidity
UN: These are the attributes that are being evaluated or measured, not the
results of the evaluation.
HL: {isa} Organism Attribute

UI: T200
STY: Clinical Drug
ABR: clnd
STN: A1.3.3
DEF: A pharmaceutical preparation as produced by the manufacturer.  The name
usually includes the substance, its strength, and the form, but may include the
substance and only one of the other two items.
MG Oral Tablet
UN: Do not double type with Pharmacologic Substance, Antibiotic, or other
chemical semantic types.
HL: {isa} Manufactured Object

UI: T077
STY: Conceptual Entity
ABR: cnce
STN: A2
DEF: A broad type for grouping abstract entities or concepts.
UN: Few concepts will be assigned to this broad type.
HL: {isa} Entity;
{inverse_isa} Organism Attribute;
{inverse_isa} Finding;
{inverse_isa} Idea or Concept;
{inverse_isa} Occupation or Discipline;
{inverse_isa} Organization;
{inverse_isa} Group;
{inverse_isa} Group Attribute;
{inverse_isa} Intellectual Product;
{inverse_isa} Language

UI: T019
STY: Congenital Abnormality
ABR: cgab
STN: A1.2.2.1
DEF: An abnormal structure, or one that is abnormal in size or location, present
at birth or evolving over time as a result of a defect in embryogenesis.
UN: If the congenital abnormality involves multiple defects then the type
'Disease or Syndrome' will also be assigned.
HL: {isa} Anatomical Abnormality

UI: T056
STY: Daily or Recreational Activity
ABR: dora
STN: B1.2
DEF: An activity carried out for recreation or exercise, or as part of daily
life.
HL: {isa} Activity

UI: T060
STY: Diagnostic Procedure
ABR: diap
STN: B1.3.1.2
DEF: A procedure, method, or technique used to determine the nature or identity
of a disease or disorder.  This excludes procedures which are primarily carried
out on specimens in a laboratory.
Rhinometry, Acoustic
HL: {isa} Health Care Activity

UI: T047
STY: Disease or Syndrome
ABR: dsyn
STN: B2.2.1.2.1
DEF: A condition which alters or interferes with a normal process, state, or
activity of an organism.  It is usually characterized by the abnormal functioning
of one or more of the host's systems, parts, or organs.  Included here is a
complex of symptoms descriptive of a disorder.
Syndrome
UN: Any specific disease or syndrome that is modified by such modifiers as
"acute", "prolonged", etc.  will also be assigned to this type.  If an anatomic
abnormality has a pathologic manifestation, then it will be given this type as
well as a type from the 'Anatomical Abnormality' hierarchy, e.g., "Diabetic
Cataract" will be double-typed for this reason.
HL: {isa} Pathologic Function;
{inverse_isa} Mental or Behavioral Dysfunction;
{inverse_isa} Neoplastic Process

UI: T203
STY: Drug Delivery Device
ABR: drdd
STN: A1.3.1.1
DEF: A medical device that contains a clinical drug or drugs.
Pak
HL: {isa} Medical Device

UI: T065
STY: Educational Activity
ABR: edac
STN: B1.3.4
DEF: An activity related to the organization and provision of education.
HL: {isa} Occupational Activity

UI: T111
STY: Eicosanoid
ABR: eico
STN: A1.4.1.2.1.9.2
DEF: An oxygenated metabolite from polyunsaturated 20 carbon fatty acids
including lipoxygenase and cyclooxygenase products and their synthetic analogs.
This includes the prostaglandins and thromboxanes.
UN: Naturally occurring eicosanoids will also be assigned to a type from the
'Biologically Active Substance' hierarchy.  Synthetic eicosanoids will also be
assigned to the type 'Pharmacologic Substance'.
HL: {isa} Lipid

UI: T196
STY: Element, Ion, or Isotope
ABR: elii
STN: A1.4.1.2.3
DEF: One of the 109 presently known fundamental substances that comprise all
matter at and above the atomic level.  This includes elemental metals, rare
gases, and most abundant naturally occurring radioactive elements, as well as
the ionic counterparts of elements (NA+, Cl-), and the less abundant isotopic
forms.  This does not include organic ions such as iodoacetate to which the type
'Organic Chemical' is assigned.
Uranium
UN: Group terms such as sulfates would be assigned to the type 'Chemical Viewed
Structurally'.  Substances such as aluminum chloride would be assigned the type
'Inorganic Chemical'.  Technetium Tc 99m Aggregated Albumin would not receive
this type.
HL: {isa} Chemical Viewed Structurally

UI: T018
STY: Embryonic Structure
ABR: emst
STN: A1.2.1
DEF: An anatomical structure that exists only before the organism is fully
formed; in mammals, for example, a structure that exists only prior to the birth
of the organism.  This structure may be normal or abnormal.
HL: {isa} Anatomical Structure

UI: T071
STY: Entity
ABR: enty
STN: A
DEF: A broad type for grouping physical and conceptual entities.
UN: Few concepts will be assigned to this broad type.
HL: {inverse_isa} Physical Object;
{inverse_isa} Conceptual Entity

UI: T069
STY: Environmental Effect of Humans
ABR: eehu
STN: B2.1.1
DEF: A change in the natural environment that is a result of the activities of
human beings.
HL: {isa} Human-caused Phenomenon or Process

UI: T126
STY: Enzyme
ABR: enzy
STN: A1.4.1.1.3.3
DEF: A complex chemical, usually a protein, that is produced by living cells and
which catalyzes specific biochemical reactions.  There are six main types of
enzymes: oxidoreductases, transferases, hydrolases, lyases, isomerases, and
ligases.
UN: Generally when a concept is assigned to this type, it will also be assigned
to the type 'Amino Acid, Peptide, or Protein'.
HL: {isa} Biologically Active Substance

UI: T204
STY: Eukaryote
ABR: euka
STN: A1.1.3
DEF: One of the three domains of life (the others being Bacteria and Archaea),
also called Eukarya.  These are organisms whose cells are enclosed in membranes
and possess a nucleus.  They comprise almost all multicellular and many
unicellular organisms, and are traditionally divided into groups (sometimes
called kingdoms) including Animals, Plants, Fungi, various Algae, and other taxa
that were previously part of the old kingdom Protista.
HL: {isa} Organism;
{inverse_isa} Plant;
{inverse_isa} Fungus;
{inverse_isa} Animal

UI: T051
STY: Event
ABR: evnt
STN: B
DEF: A broad type for grouping activities, processes and states.
UN: Few concepts will be assigned to this broad type.
HL: {inverse_isa} Activity;
{inverse_isa} Phenomenon or Process

UI: T050
STY: Experimental Model of Disease
ABR: emod
STN: B2.2.1.2.3
DEF: A representation in a non-human organism of a human disease for the purpose
of research into its mechanism or treatment.
HL: {isa} Pathologic Function

UI: T099
STY: Family Group
ABR: famg
STN: A2.9.3
DEF: An individual or individuals classified according to their family
relationships or relative position in the family unit.
HL: {isa} Group

UI: T033
STY: Finding
ABR: fndg
STN: A2.2
DEF: That which is discovered by direct observation or measurement of an
organism attribute or condition, including the clinical history of the patient.
The history of the presence of a disease is a 'Finding' and is distinguished
from the disease itself.
fragility; Absent tendon reflex
UN: Only in rare circumstances will findings be double-typed with either
'Pathologic Function' or 'Anatomical Abnormality'.  Most findings will be
assigned the types 'Laboratory or Test Result' or 'Sign or Symptom'.  Only those
findings that relate to patient history or to the determination of a state will
be assigned the type 'Finding'.
HL: {isa} Conceptual Entity;
{inverse_isa} Laboratory or Test Result;
{inverse_isa} Sign or Symptom

UI: T013
STY: Fish
ABR: fish
STN: A1.1.3.1.1.3
DEF: A cold-blooded aquatic vertebrate characterized by fins and breathing by
gills.  Included here are fishes having either a bony skeleton, such as a perch,
or a cartilaginous skeleton, such as a shark, or those lacking a jaw, such as a
lamprey or hagfish.
HL: {isa} Vertebrate

UI: T168
STY: Food
ABR: food
STN: A1.4.3
DEF: Any substance generally containing nutrients, such as carbohydrates,
proteins, and fats, that can be ingested by a living organism and metabolized
into energy and body tissue.  Some foods are naturally occurring, others are
either partially or entirely made by humans.
UN: Food additives, food preservatives, and food dyes should be given the type
'Chemical Viewed Functionally'; "Diet Coke" would be assigned this type.
HL: {isa} Substance

UI: T021
STY: Fully Formed Anatomical Structure
ABR: ffas
STN: A1.2.3
DEF: An anatomical structure in a fully formed organism; in mammals, for
example, a structure in the body after the birth of the organism.
UN: Few concepts will be assigned to this broad type.
HL: {isa} Anatomical Structure;
{inverse_isa} Body Part, Organ, or Organ Component;
{inverse_isa} Tissue;
{inverse_isa} Cell;
{inverse_isa} Cell Component;
{inverse_isa} Gene or Genome

UI: T169
STY: Functional Concept
ABR: ftcn
STN: A2.1.4
DEF: A concept which is of interest because it pertains to the carrying out of a
process or activity.
HL: {isa} Idea or Concept;
{inverse_isa} Body System

UI: T004
STY: Fungus
ABR: fngs
STN: A1.1.3.2
DEF: A eukaryotic organism characterized by the absence of chlorophyll and the
presence of a rigid cell wall.  Included here are both slime molds and true fungi
such as yeasts, molds, mildews, and mushrooms.
HL: {isa} Eukaryote

UI: T028
STY: Gene or Genome
ABR: gngm
STN: A1.2.3.5
DEF: A specific sequence, or in the case of the genome the complete sequence, of
nucleotides along a molecule of DNA or RNA (in the case of some viruses) which
represent the functional units of heredity.
HL: {isa} Fully Formed Anatomical Structure

UI: T045
STY: Genetic Function
ABR: genf
STN: B2.2.1.1.4.1
DEF: Functions of or related to the maintenance, translation or expression of
the genetic material.
HL: {isa} Molecular Function

UI: T083
STY: Geographic Area
ABR: geoa
STN: A2.1.5.4
DEF: A geographic location, generally having definite boundaries.
HL: {isa} Spatial Concept

UI: T064
STY: Governmental or Regulatory Activity
ABR: gora
STN: B1.3.3
DEF: An activity carried out by officially constituted governments, or an
activity related to the creation or enforcement of the rules or regulations
governing some field of endeavor.
Assistance
HL: {isa} Occupational Activity

UI: T096
STY: Group
ABR: grup
STN: A2.9
DEF: A conceptual entity referring to the classification of individuals
according to certain shared characteristics.
UN: Few concepts will be assigned to this broad type.
HL: {isa} Conceptual Entity;
{inverse_isa} Professional or Occupational Group;
{inverse_isa} Population Group;
{inverse_isa} Family Group;
{inverse_isa} Age Group;
{inverse_isa} Patient or Disabled Group

UI: T102
STY: Group Attribute
ABR: grpa
STN: A2.8
DEF: A conceptual entity which refers to the frequency or distribution of
certain characteristics or phenomena in certain groups.
HL: {isa} Conceptual Entity

UI: T131
STY: Hazardous or Poisonous Substance
ABR: hops
STN: A1.4.1.1.5
DEF: A substance of concern because of its potentially hazardous or toxic
effects.  This would include most drugs of abuse, as well as agents that require
special handling because of their toxicity.
UN: Most pharmaceutical agents, although potentially harmful, are excluded here
and are assigned to the type 'Pharmacologic Substance'.  All pesticides are
assigned to this type.
HL: {isa} Chemical Viewed Functionally

UI: T058
STY: Health Care Activity
ABR: hlca
STN: B1.3.1
DEF: An activity of or relating to the practice of medicine or involving the
care of patients.
HL: {isa} Occupational Activity;
{inverse_isa} Laboratory Procedure;
{inverse_isa} Diagnostic Procedure;
{inverse_isa} Therapeutic or Preventive Procedure

UI: T093
STY: Health Care Related Organization
ABR: hcro
STN: A2.7.1
DEF: An established organization which carries out specific functions related to
health care delivery or research in the life sciences.
Organization
UN: Concepts for health care related professional societies are assigned the
type 'Professional Society'.
HL: {isa} Organization

UI: T125
STY: Hormone
ABR: horm
STN: A1.4.1.1.3.2
DEF: In animals, a chemical usually secreted by an endocrine gland whose
products are released into the circulating fluid.  Hormones act as chemical
messengers and regulate various physiologic processes such as growth,
reproduction, metabolism, etc.  They usually fall into two broad classes, steroid
hormones and peptide hormones.
UN: Synthetic hormones that are used as drugs should receive this type and
'Pharmacologic Substance'.  Plant hormones are assigned only to the type
'Pharmacologic Substance'.
HL: {isa} Biologically Active Substance

UI: T016
STY: Human
ABR: humn
STN: A1.1.3.1.1.4.1
DEF: Modern man, the only remaining species of the Homo genus.
UN: If a concept describes a human being from the point of view of occupational,
family, social status, etc., then a type from the 'Group' hierarchy will be
assigned instead.
HL: {isa} Mammal

UI: T068
STY: Human-caused Phenomenon or Process
ABR: hcpp
STN: B2.1
DEF: A phenomenon or process that is a result of the activities of human beings.
UN: If the concept refers to the activity itself, rather than the result of that
activity, a type from the 'Activity' hierarchy will be assigned instead.
HL: {isa} Phenomenon or Process;
{inverse_isa} Environmental Effect of Humans

UI: T078
STY: Idea or Concept
ABR: idcn
STN: A2.1
DEF: An abstract concept, such as a social, religious or philosophical concept.
HL: {isa} Conceptual Entity;
{inverse_isa} Temporal Concept;
{inverse_isa} Qualitative Concept;
{inverse_isa} Quantitative Concept;
{inverse_isa} Spatial Concept;
{inverse_isa} Functional Concept

UI: T129
STY: Immunologic Factor
ABR: imft
STN: A1.4.1.1.3.5
DEF: A biologically active substance whose activities affect or play a role in
the functioning of the immune system.
UN: Antigens and antibodies are assigned to this type.  Unlike most biologically
active substances, some immunologic factors may be exogenous.  Vaccines should be
given this type and the type 'Pharmacologic Substance'.
HL: {isa} Biologically Active Substance

UI: T130
STY: Indicator, Reagent, or Diagnostic Aid
ABR: irda
STN: A1.4.1.1.4
DEF: A substance primarily of interest for its use in laboratory or diagnostic
tests and procedures to detect, measure, examine, or analyze other chemicals,
processes, or conditions.
UN: Radioactive imaging agents should be assigned to this type and not to the
type 'Pharmacologic Substance' unless they are also being used therapeutically.
HL: {isa} Chemical Viewed Functionally

UI: T055
STY: Individual Behavior
ABR: inbe
STN: B1.1.2
DEF: Behavior exhibited by a human or an animal that is not a direct result of
interaction with other members of the species, but which may have an effect on
others.
UN: 'Individual Behavior' is carried out by an individual, though others may be
present, and is, thus, distinguished from 'Social Behavior' which requires the
direct participation of others.
HL: {isa} Behavior

UI: T037
STY: Injury or Poisoning
ABR: inpo
STN: B2.3
DEF: A traumatic wound, injury, or poisoning caused by an external agent or
force.
Snake Bites
UN: An `Injury or Poisoning' is distinguished from a 'Disease or Syndrome' that
may be a result of prolonged exposure to toxic materials.
HL: {isa} Phenomenon or Process

UI: T197
STY: Inorganic Chemical
ABR: inch
STN: A1.4.1.2.2
DEF: Chemical elements and their compounds, excluding the hydrocarbons and their
derivatives (except carbides, carbonates, cyanides, cyanates and carbon
disulfide).  Generally inorganic compounds contain ionic bonds.  Included here are
inorganic acids and salts, alloys, alkalies, and minerals.
HL: {isa} Chemical Viewed Structurally

UI: T170
STY: Intellectual Product
ABR: inpr
STN: A2.4
DEF: A conceptual entity resulting from human endeavor.  Concepts assigned to
this type generally refer to information created by humans for some purpose.
Forecast
UN: Concepts referring to theorems, models, and systems are assigned here.  In
some cases, a concept may be assigned to both 'Intellectual Product' and
'Research Activity'.  For example, the concept "Comparative Study" might be
viewed as both an activity and the result, or product, of that activity.
HL: {isa} Conceptual Entity;
{inverse_isa} Regulation or Law;
{inverse_isa} Classification

UI: T034
STY: Laboratory or Test Result
ABR: lbtr
STN: A2.2.1
DEF: The outcome of a specific test to measure an attribute or to determine the
presence, absence, or degree of a condition.
UN: Laboratory or test results are considered inherently quantitative and, thus,
are not assigned the additional type 'Quantitative Concept'.
HL: {isa} Finding

UI: T059
STY: Laboratory Procedure
ABR: lbpr
STN: B1.3.1.1
DEF: A procedure, method, or technique used to determine the composition,
quantity, or concentration of a specimen, and which is carried out in a clinical
laboratory.  Included here are procedures which measure the times and rates of
reactions.
calculation
HL: {isa} Health Care Activity

UI: T171
STY: Language
ABR: lang
STN: A2.5
DEF: The system of communication used by a particular nation or people.
HL: {isa} Conceptual Entity

UI: T119
STY: Lipid
ABR: lipd
STN: A1.4.1.2.1.9
DEF: An inclusive group of fat or fat-derived substances that are soluble in
nonpolar solvents related to fatty acid esters, fatty alcohols, sterols, waxes,
etc.  Included in this group are the saponifiable lipids such as glycerides (fats
and oils), essential (volatile) oils, and phospholipids.
UN: Phospholipids should not also be typed with 'Organophosphorus Compound'.
Fatty acids are composed of a chain of alkyl groups containing from 4-22 carbon
atoms (usually even-numbered) and characterized by a terminal carboxyl group.
HL: {isa} Organic Chemical;
{inverse_isa} Steroid;
{inverse_isa} Eicosanoid

UI: T066
STY: Machine Activity
ABR: mcha
STN: B1.4
DEF: An activity carried out primarily or exclusively by machines.
Processing
HL: {isa} Activity

UI: T015
STY: Mammal
ABR: mamm
STN: A1.1.3.1.1.4
DEF: A vertebrate having a constant body temperature and characterized by the
presence of hair, mammary glands and sweat glands.
HL: {isa} Vertebrate;
{inverse_isa} Human

UI: T073
STY: Manufactured Object
ABR: mnob
STN: A1.3
DEF: A physical object made by human beings.
HL: {isa} Physical Object;
{inverse_isa} Medical Device;
{inverse_isa} Research Device;
{inverse_isa} Clinical Drug

UI: T074
STY: Medical Device
ABR: medd
STN: A1.3.1
DEF: A manufactured object used primarily in the diagnosis, treatment, or
prevention of physiologic or anatomic disorders.
UN: A medical device may be used for research purposes, but since its primary
use is for routine medical care, it is distinguished from a 'Research Device'
which is used primarily for research purposes.
HL: {isa} Manufactured Object;
{inverse_isa} Drug Delivery Device

UI: T048
STY: Mental or Behavioral Dysfunction
ABR: mobd
STN: B2.2.1.2.1.1
DEF: A clinically significant dysfunction whose major manifestation is
behavioral or psychological.  These dysfunctions may have identified or presumed
biological etiologies or manifestations.
HL: {isa} Disease or Syndrome

UI: T041
STY: Mental Process
ABR: menp
STN: B2.2.1.1.1.1
DEF: A physiologic function involving the mind or cognitive processing.
HL: {isa} Organism Function

UI: T063
STY: Molecular Biology Research Technique
ABR: mbrt
STN: B1.3.2.1
DEF: Any of the techniques used in the study of or the directed modification of
the gene complement of a living organism.
Determination, Sequence Homology
HL: {isa} Research Activity

UI: T044
STY: Molecular Function
ABR: moft
STN: B2.2.1.1.4
DEF: A physiologic function occurring at the molecular level.
HL: {isa} Physiologic Function;
{inverse_isa} Genetic Function

UI: T085
STY: Molecular Sequence
ABR: mosq
STN: A2.1.5.3
DEF: A broad type for grouping the collected sequences of amino acids,
carbohydrates, and nucleotide sequences.  Descriptions of these sequences are
generally reported in the published literature and/or are deposited in and
maintained by databanks such as GenBank, European Molecular Biology Laboratory
(EMBL), National Biomedical Research Foundation (NBRF), or other sequence
repositories.
HL: {isa} Spatial Concept;
{inverse_isa} Nucleotide Sequence;
{inverse_isa} Amino Acid Sequence;
{inverse_isa} Carbohydrate Sequence

UI: T070
STY: Natural Phenomenon or Process
ABR: npop
STN: B2.2
DEF: A phenomenon or process that occurs irrespective of the activities of human
beings.
HL: {isa} Phenomenon or Process;
{inverse_isa} Biologic Function

UI: T191
STY: Neoplastic Process
ABR: neop
STN: B2.2.1.2.1.2
DEF: A new and abnormal growth of tissue in which the growth is uncontrolled and
progressive.  The growths may be malignant or benign.
UN: All neoplasms are assigned to this type.  Do not also assign a type from the
'Anatomical Abnormality' hierarchy.
HL: {isa} Disease or Syndrome

UI: T124
STY: Neuroreactive Substance or Biogenic Amine
ABR: nsba
STN: A1.4.1.1.3.1
DEF: An endogenous substance whose activities affect or play an important role
in the functioning of the nervous system.  Included here are catecholamines,
neuroregulators, neurophysins, etc.
UN: Unlike many of the other types under 'Biologically Active Substance', do not
assign this type to drugs that are used on the nervous system unless the
compound is endogenous.
HL: {isa} Biologically Active Substance

UI: T114
STY: Nucleic Acid, Nucleoside, or Nucleotide
ABR: nnon
STN: A1.4.1.2.1.5
DEF: A complex compound of high molecular weight occurring in living cells.
These are basically of two types, ribonucleic (RNA) and deoxyribonucleic (DNA)
acids.  Nucleic acids are made of nucleotides (nitrogen-containing base, a
5-carbon sugar, and one or more phosphate group) linked together by a
phosphodiester bond between the 5' and 3' carbon atoms.  Nucleosides are
compounds composed of a purine or pyrimidine base (usually adenine, cytosine,
guanine, thymine, uracil) linked to either a ribose or a deoxyribose sugar.
UN: If this type has been assigned, the type 'Organophosphorus Compound' will
not also be assigned.  Naturally occurring nucleic acids, nucleosides, or
nucleotides will also be assigned a type from the 'Biologically Active
Substance' hierarchy.
HL: {isa} Organic Chemical

UI: T086
STY: Nucleotide Sequence
ABR: nusq
STN: A2.1.5.3.1
DEF: The sequence of purines and pyrimidines in nucleic acids and
polynucleotides.  Included here are nucleotide-rich regions, conserved sequence,
and DNA transforming region.
HL: {isa} Molecular Sequence

UI: T090
STY: Occupation or Discipline
ABR: ocdi
STN: A2.6
DEF: A vocation, academic discipline, or field of study, or a subpart of an
occupation or discipline.
UN: If the concept refers to the individuals who have the vocation, the type
'Professional or Occupational Group' will be assigned instead.
HL: {isa} Conceptual Entity;
{inverse_isa} Biomedical Occupation or Discipline

UI: T057
STY: Occupational Activity
ABR: ocac
STN: B1.3
DEF: An activity carried out as part of an occupation or job.
HL: {isa} Activity;
{inverse_isa} Health Care Activity;
{inverse_isa} Research Activity;
{inverse_isa} Governmental or Regulatory Activity;
{inverse_isa} Educational Activity

UI: T042
STY: Organ or Tissue Function
ABR: ortf
STN: B2.2.1.1.2
DEF: A physiologic function of a particular organ, organ system, or tissue.
HL: {isa} Physiologic Function

UI: T109
STY: Organic Chemical
ABR: orch
STN: A1.4.1.2.1
DEF: The general class of carbon-containing compounds, usually based on carbon
chains or rings, and also containing hydrogen (hydrocarbons), with or without
nitrogen, oxygen, or other elements in which the bonding between elements is
generally covalent.
UN: Salts of organic chemicals (such as Calcium Acetate) would be considered
organic chemicals and should not also receive the type 'Inorganic Chemical'.
HL: {isa} Chemical Viewed Structurally;
{inverse_isa} Nucleic Acid, Nucleoside, or Nucleotide;
{inverse_isa} Organophosphorus Compound;
{inverse_isa} Amino Acid, Peptide, or Protein;
{inverse_isa} Carbohydrate;
{inverse_isa} Lipid

UI: T001
STY: Organism
ABR: orgm
STN: A1.1
DEF: Generally, a living individual, including all plants and animals.
HL: {isa} Physical Object;
{inverse_isa} Virus;
{inverse_isa} Bacterium;
{inverse_isa} Archaeon;
{inverse_isa} Eukaryote

UI: T032
STY: Organism Attribute
ABR: orga
STN: A2.3
DEF: A property of the organism or its major parts.
NH: Y
HL: {isa} Conceptual Entity;
{inverse_isa} Clinical Attribute

UI: T040
STY: Organism Function
ABR: orgf
STN: B2.2.1.1.1
DEF: A physiologic function of the organism as a whole, of multiple organ
systems, or of multiple organs or tissues.
HL: {isa} Physiologic Function;
{inverse_isa} Mental Process

UI: T092
STY: Organization
ABR: orgt
STN: A2.7
DEF: The result of uniting for a common purpose or function.  The continued
existence of an organization is not dependent on any of its members, its
location, or particular facility.  Components or subparts of organizations are
also included here.  Although the names of organizations are sometimes used to
refer to the buildings in which they reside, they are not inherently physical in
nature.
Universities; European Common Market
HL: {isa} Conceptual Entity;
{inverse_isa} Health Care Related Organization;
{inverse_isa} Professional Society;
{inverse_isa} Self-help or Relief Organization

UI: T115
STY: Organophosphorus Compound
ABR: opco
STN: A1.4.1.2.1.6
DEF: An organic compound containing phosphorus as a constituent.  Included here
are organic phosphinic, phosphonic and phosphoric acid derivatives and their
thiophosphorus counterparts.  Excluded are phospholipids, sugar phosphates,
phosphoproteins, nucleotides, and nucleic acids.
Triphosphate
HL: {isa} Organic Chemical

UI: T046
STY: Pathologic Function
ABR: patf
STN: B2.2.1.2
DEF: A disordered process, activity, or state of the organism as a whole, of a
body system or systems, or of multiple organs or tissues.  Included here are
normal responses to a negative stimulus as well as patholologic conditions or
states that are less specific than a disease.  Pathologic functions frequently
have systemic effects.
UN: If the process is specific, for example to a site or substance, then
'Disease or Syndrome' will be assigned and not 'Pathologic Function'.  For
example, "cerebral anoxia", "brain edema", and "milk hypersensitivity" will all
be assigned to 'Disease or Syndrome' only.
HL: {isa} Biologic Function;
{inverse_isa} Disease or Syndrome;
{inverse_isa} Cell or Molecular Dysfunction;
{inverse_isa} Experimental Model of Disease

UI: T101
STY: Patient or Disabled Group
ABR: podg
STN: A2.9.5
DEF: An individual or individuals classified according to a disability, disease,
condition or treatment.
HL: {isa} Group

UI: T121
STY: Pharmacologic Substance
ABR: phsu
STN: A1.4.1.1.1
DEF: A substance used in the treatment or prevention of pathologic disorders.
This includes substances that occur naturally in the body and are administered
therapeutically.
UN: If a substance is both endogenous and typically used as a drug, then this
type and the type 'Biologically Active Substance' or one of its children are
assigned.  Body substances that are used therapeutically such as whole blood
preparation, NOS would only receive the type 'Body Substance'.  Substances used
in the diagnosis or analysis of normal and abnormal body functions should be
given the type 'Indicator, Reagent, or Diagnostic Aid'.
HL: {isa} Chemical Viewed Functionally;
{inverse_isa} Antibiotic

UI: T067
STY: Phenomenon or Process
ABR: phpr
STN: B2
DEF: A process or state which occurs naturally or as a result of an activity.
HL: {isa} Event;
{inverse_isa} Injury or Poisoning;
{inverse_isa} Human-caused Phenomenon or Process;
{inverse_isa} Natural Phenomenon or Process

UI: T072
STY: Physical Object
ABR: phob
STN: A1
DEF: An object perceptible to the sense of vision or touch.
HL: {isa} Entity;
{inverse_isa} Organism;
{inverse_isa} Anatomical Structure;
{inverse_isa} Manufactured Object;
{inverse_isa} Substance

UI: T039
STY: Physiologic Function
ABR: phsf
STN: B2.2.1.1
DEF: A normal process, activity, or state of the body.
HL: {isa} Biologic Function;
{inverse_isa} Organism Function;
{inverse_isa} Organ or Tissue Function;
{inverse_isa} Cell Function;
{inverse_isa} Molecular Function

UI: T002
STY: Plant
ABR: plnt
STN: A1.1.3.3
DEF: An organism having cellulose cell walls, growing by synthesis of inorganic
substances, generally distinguished by the presence of chlorophyll, and lacking
the power of locomotion.  Plant parts are included here as well.
HL: {isa} Eukaryote

UI: T098
STY: Population Group
ABR: popg
STN: A2.9.2
DEF: An indivdual or individuals classified according to their sex, racial
origin, religion, common place of living, financial or social status, or some
other cultural or behavioral attribute.
HL: {isa} Group

UI: T097
STY: Professional or Occupational Group
ABR: prog
STN: A2.9.1
DEF: An individual or individuals classified according to their vocation.
Zoologist
UN: If the concept refers to the discipline or vocation itself, rather than to
the individuals who have the vocation, then the type 'Occupation or Discipline'
will be assigned instead.
HL: {isa} Group

UI: T094
STY: Professional Society
ABR: pros
STN: A2.7.2
DEF: An organization uniting those who have a common vocation or who are
involved with a common field of study.
Associations
HL: {isa} Organization

UI: T080
STY: Qualitative Concept
ABR: qlco
STN: A2.1.2
DEF: A concept which is an assessment of some quality, rather than a direct
measurement.
HL: {isa} Idea or Concept

UI: T081
STY: Quantitative Concept
ABR: qnco
STN: A2.1.3
DEF: A concept which involves the dimensions, quantity or capacity of something
using some unit of measure, or which involves the quantitative comparison of
entities.
UN: If the concept refers to rate or distribution, the type 'Temporal Concept'
is not also assigned.
HL: {isa} Idea or Concept

UI: T192
STY: Receptor
ABR: rcpt
STN: A1.4.1.1.3.6
DEF: A specific structure or site on the cell surface or within its cytoplasm
that recognizes and binds with other specific molecules.  These include the
proteins on the surface of an immunocompetent cell that binds with antigens, or
proteins found on the surface molecules that bind with hormones or
neurotransmitters and react with other molecules that respond in a specific way.
HL: {isa} Biologically Active Substance

UI: T089
STY: Regulation or Law
ABR: rnlw
STN: A2.4.2
DEF: An intellectual product resulting from legislative or regulatory activity.
HL: {isa} Intellectual Product

UI: T014
STY: Reptile
ABR: rept
STN: A1.1.3.1.1.5
DEF: A cold-blooded vertebrate having an external covering of scales or horny
plates.  Reptiles breathe by means of lungs and are generally egg-laying.
HL: {isa} Vertebrate

UI: T062
STY: Research Activity
ABR: resa
STN: B1.3.2
DEF: An activity carried out as part of research or experimentation.
UN: In some cases, a concept may be assigned to both this type and the type
'Intellectual Product'.  For example, the concept "Comparative Study" might be
viewed as both an activity and the result, or product, of that activity.
HL: {isa} Occupational Activity;
{inverse_isa} Molecular Biology Research Technique

UI: T075
STY: Research Device
ABR: resd
STN: A1.3.2
DEF: A manufactured object used primarily in carrying out scientific research or
experimentation.
UN: A research device is distinguished from a 'Medical Device', which though it
may be used for research purposes is used primarily for routine medical care.
HL: {isa} Manufactured Object

UI: T095
STY: Self-help or Relief Organization
ABR: shro
STN: A2.7.3
DEF: An organization whose purpose and function is to provide assistance to the
needy or to offer support to those sharing similar problems.
HL: {isa} Organization

UI: T184
STY: Sign or Symptom
ABR: sosy
STN: A2.2.2
DEF: An observable manifestation of a disease or condition based on clinical
judgment, or a manifestation of a disease or condition which is experienced by
the patient and reported as a subjective observation.
HL: {isa} Finding

UI: T054
STY: Social Behavior
ABR: socb
STN: B1.1.1
DEF: Behavior that is a direct result or function of the interaction of humans
or animals with their fellows.  This includes behavior that may be considered
anti-social.
Conformity
UN: 'Social Behavior' requires the direct participation of others and is, thus,
distinguished from 'Individual Behavior' which is carried out by an individual,
though others may be present.
HL: {isa} Behavior

UI: T082
STY: Spatial Concept
ABR: spco
STN: A2.1.5
DEF: A location, region, or space, generally having definite boundaries.
HL: {isa} Idea or Concept;
{inverse_isa} Body Location or Region;
{inverse_isa} Body Space or Junction;
{inverse_isa} Geographic Area;
{inverse_isa} Molecular Sequence

UI: T110
STY: Steroid
ABR: strd
STN: A1.4.1.2.1.9.1
DEF: One of a group of polycyclic, 17-carbon-atom, fused-ring compounds
occurring both in natural and synthetic forms.  Included here are naturally
occurring and synthetic steroids, bufanolides, cardanolides, homosteroids,
norsteroids, and secosteroids.
HL: {isa} Lipid

UI: T167
STY: Substance
ABR: sbst
STN: A1.4
DEF: A material with definite or fairly definite chemical composition.
HL: {isa} Physical Object;
{inverse_isa} Body Substance;
{inverse_isa} Chemical;
{inverse_isa} Food

UI: T079
STY: Temporal Concept
ABR: tmco
STN: A2.1.1
DEF: A concept which pertains to time or duration.
UN: If the concept refers to a phase, stage, cycle, interval, period, or rhythm,
it is assigned to this type.
HL: {isa} Idea or Concept

UI: T061
STY: Therapeutic or Preventive Procedure
ABR: topp
STN: B1.3.1.3
DEF: A procedure, method, or technique designed to prevent a disease or a
disorder, or to improve physical function, or used in the process of treating a
disease or injury.
HL: {isa} Health Care Activity

UI: T024
STY: Tissue
ABR: tisu
STN: A1.2.3.2
DEF: An aggregation of similarly specialized cells and the associated
intercellular substance.  Tissues are relatively non-localized in comparison to
body parts, organs or organ components.
HL: {isa} Fully Formed Anatomical Structure

UI: T010
STY: Vertebrate
ABR: vtbt
STN: A1.1.3.1.1
DEF: An animal which has a spinal column.
UN: Few concepts will be assigned to this broad type.
HL: {isa} Animal;
{inverse_isa} Amphibian;
{inverse_isa} Bird;
{inverse_isa} Fish;
{inverse_isa} Reptile;
{inverse_isa} Mammal

UI: T005
STY: Virus
ABR: virs
STN: A1.1.4
DEF: An organism consisting of a core of a single nucleic acid enclosed in a
protective coat of protein.  A virus may replicate only inside a host living
cell.  A virus exhibits some but not all of the usual characteristics of living
things.
HL: {isa} Organism

UI: T127
STY: Vitamin
ABR: vita
STN: A1.4.1.1.3.4
DEF: A substance, usually an organic chemical complex, present in natural
products or made synthetically, which is essential in the diet of man or other
higher animals.  Included here are vitamin precursors, provitamins, and vitamin
supplements.
UN: Essential amino acids are not assigned to this type.  They will be assigned
to the type 'Amino Acid, Peptide, or Protein'.  This can be used with
'Pharmacologic Substance' if the compound is being administered therapeutically
or if the source has it classified as therapeutic (i.e., N'ICE Sugarless Vitamin
C Drops).
HL: {isa} Biologically Active Substance

UI: T173
RL: adjacent_to
ABR: AD
RIN: adjacent_to
RTN: R2.2
DEF: Close to, near or abutting another physical unit with no other structure of
the same kind intervening.  This includes adjoins, abuts, is contiguous to, is
juxtaposed, and is close to.
HL: {isa} spatially_related_to
STL: [Body Location or Region|Body Location or Region];
[Body Location or Region|Body Part, Organ, or Organ Component];
[Body Location or Region|Body Space or Junction];
[Body Part, Organ, or Organ Component|Body Part, Organ, or Organ Component];
[Body Part, Organ, or Organ Component|Body Space or Junction];
[Body Part, Organ, or Organ Component|Cell];
[Body Part, Organ, or Organ Component|Tissue];
[Body Space or Junction|Body Space or Junction];
[Cell Component|Body Space or Junction];
[Cell Component|Cell Component];
[Cell|Cell];
[Tissue|Body Space or Junction];
[Tissue|Tissue]

UI: T151
RL: affects
ABR: AF
RIN: affected_by
RTN: R3.1
DEF: Produces a direct effect on.  Implied here is the altering or influencing of
an existing condition, state, situation, or entity.  This includes has a role in,
alters, influences, predisposes, catalyzes, stimulates, regulates, depresses,
impedes, enhances, contributes to, leads to, and modifies.
HL: {isa} functionally_related_to;
{inverse_isa} interacts_with;
{inverse_isa} disrupts;
{inverse_isa} prevents;
{inverse_isa} complicates;
{inverse_isa} manages;
{inverse_isa} treats
STL: [Anatomical Abnormality|Organism];
[Anatomical Abnormality|Physiologic Function];
[Behavior|Behavior];
[Behavior|Mental Process];
[Biologic Function|Organism];
[Cell Component|Physiologic Function];
[Chemical|Natural Phenomenon or Process];
[Diagnostic Procedure|Patient or Disabled Group];
[Food|Biologic Function];
[Gene or Genome|Physiologic Function];
[Health Care Activity|Biologic Function];
[Mental or Behavioral Dysfunction|Behavior];
[Mental Process|Behavior];
[Natural Phenomenon or Process|Natural Phenomenon or Process];
[Physiologic Function|Organism Attribute];
[Regulation or Law|Group];
[Regulation or Law|Organization];
[Research Activity|Mental Process];
[Therapeutic or Preventive Procedure|Patient or Disabled Group]

UI: T193
RL: analyzes
ABR: AN
RIN: analyzed_by
RTN: R5.3
DEF: Studies or examines using established quantitative or qualitative methods.
HL: {isa} conceptually_related_to;
{inverse_isa} assesses_effect_of
STL: [Diagnostic Procedure|Body Substance];
[Diagnostic Procedure|Chemical];
[Laboratory Procedure|Body Substance];
[Laboratory Procedure|Chemical]

UI: T164
RL: assesses_effect_of
ABR: AE
RIN: assessed_for_effect_by
RTN: R5.3.1
DEF: Analyzes the influence or consequences of the function or action of.
HL: {isa} analyzes
STL: [Diagnostic Procedure|Chemical];
[Laboratory Procedure|Chemical];
[Laboratory Procedure|Natural Phenomenon or Process]

UI: T166
RL: associated_with
ABR: AW
RIN: associated_with
RTN: R
DEF: has a significant or salient relationship to.
HL: {inverse_isa} physically_related_to;
{inverse_isa} temporally_related_to;
{inverse_isa} functionally_related_to;
{inverse_isa} conceptually_related_to;
{inverse_isa} spatially_related_to
STL: [Anatomical Abnormality|Organism Attribute];
[Behavior|Geographic Area];
[Behavior|Group Attribute];
[Behavior|Group];
[Behavior|Occupation or Discipline];
[Behavior|Organism Attribute];
[Biologically Active Substance|Virus];
[Daily or Recreational Activity|Anatomical Abnormality];
[Daily or Recreational Activity|Injury or Poisoning];
[Daily or Recreational Activity|Pathologic Function];
[Finding|Anatomical Abnormality];
[Finding|Injury or Poisoning];
[Finding|Pathologic Function];
[Geographic Area|Anatomical Abnormality];
[Geographic Area|Injury or Poisoning];
[Geographic Area|Pathologic Function];
[Individual Behavior|Anatomical Abnormality];
[Individual Behavior|Injury or Poisoning];
[Individual Behavior|Pathologic Function];
[Injury or Poisoning|Organism Attribute];
[Occupational Activity|Anatomical Abnormality];
[Occupational Activity|Injury or Poisoning];
[Occupational Activity|Pathologic Function];
[Organism Attribute|Organism Attribute];
[Pathologic Function|Organism Attribute];
[Pathologic Function|Pathologic Function];
[Population Group|Anatomical Abnormality];
[Population Group|Injury or Poisoning];
[Population Group|Pathologic Function]

UI: T198
RL: branch_of
ABR: BR
RIN: has_branch
RTN: R1.6
DEF: Arises from the division of.  For example, the arborization of arteries.
HL: {isa} physically_related_to
STL: [Body Part, Organ, or Organ Component|Body Part, Organ, or Organ Component]

UI: T187
RL: brings_about
ABR: BA
RIN: brought_about_by
RTN: R3.2
DEF: Acts on or influences an entity.
HL: {isa} functionally_related_to;
{inverse_isa} produces;
{inverse_isa} causes
STL: <none>

UI: T141
RL: carries_out
ABR: CO
RIN: carried_out_by
RTN: R3.3.1
DEF: Executes a function or performs a procedure or activity.  This includes
transacts, operates on, handles, and executes.
HL: {isa} performs
STL: [Gene or Genome|Molecular Function];
[Organization|Occupational Activity]

UI: T147
RL: causes
ABR: CA
RIN: caused_by
RTN: R3.2.2
DEF: Brings about a condition or an effect.  Implied here is that an agent, such
as for example, a pharmacologic substance or an organism, has brought about the
effect.  This includes induces, effects, evokes, and etiology.
HL: {isa} brings_about
STL: [Bacterium|Pathologic Function];
[Fungus|Pathologic Function];
[Manufactured Object|Anatomical Abnormality];
[Manufactured Object|Injury or Poisoning];
[Manufactured Object|Pathologic Function];
[Substance|Anatomical Abnormality];
[Substance|Injury or Poisoning];
[Substance|Pathologic Function];
[Virus|Pathologic Function]

UI: T137
RL: co-occurs_with
ABR: CW
RIN: co-occurs_with
RTN: R4.1
DEF: Occurs at the same time as, together with, or jointly.  This includes is
co-incident with, is concurrent with, is contemporaneous with, accompanies,
coexists with, and is concomitant with.
HL: {isa} temporally_related_to
STL: [Acquired Abnormality|Injury or Poisoning];
[Anatomical Abnormality|Anatomical Abnormality];
[Finding|Finding];
[Injury or Poisoning|Injury or Poisoning];
[Pathologic Function|Anatomical Abnormality];
[Pathologic Function|Injury or Poisoning];
[Pathologic Function|Pathologic Function];
[Physiologic Function|Physiologic Function]

UI: T149
RL: complicates
ABR: CM
RIN: complicated_by
RTN: R3.1.4
DEF: Causes to become more severe or complex or results in adverse effects.
HL: {isa} affects
STL: [Anatomical Abnormality|Anatomical Abnormality];
[Biologically Active Substance|Anatomical Abnormality];
[Biologically Active Substance|Biologic Function];
[Biologically Active Substance|Injury or Poisoning];
[Hazardous or Poisonous Substance|Anatomical Abnormality];
[Hazardous or Poisonous Substance|Biologic Function];
[Hazardous or Poisonous Substance|Injury or Poisoning];
[Injury or Poisoning|Anatomical Abnormality];
[Injury or Poisoning|Pathologic Function];
[Pathologic Function|Anatomical Abnormality];
[Pathologic Function|Injury or Poisoning];
[Pathologic Function|Pathologic Function];
[Pharmacologic Substance|Anatomical Abnormality];
[Pharmacologic Substance|Biologic Function];
[Pharmacologic Substance|Injury or Poisoning];
[Therapeutic or Preventive Procedure|Biologic Function]

UI: T160
RL: conceptual_part_of
ABR: CP
RIN: has_conceptual_part
RTN: R5.11
DEF: Conceptually a portion, division, or component of some larger whole.
INH: N
HL: {isa} conceptually_related_to
STL: [Body Location or Region|Body Location or Region];
[Body Location or Region|Body System];
[Body Location or Region|Fully Formed Anatomical Structure];
[Body Part, Organ, or Organ Component|Body System];
[Body Space or Junction|Body System];
[Body Space or Junction|Fully Formed Anatomical Structure];
[Body Substance|Body System];
[Body System|Body System];
[Body System|Fully Formed Anatomical Structure];
[Cell Component|Body System];
[Cell|Body System];
[Idea or Concept|Behavior];
[Intellectual Product|Diagnostic Procedure];
[Intellectual Product|Intellectual Product];
[Laboratory or Test Result|Laboratory or Test Result];
[Occupation or Discipline|Occupation or Discipline];
[Organ or Tissue Function|Temporal Concept];
[Organism Function|Temporal Concept];
[Quantitative Concept|Therapeutic or Preventive Procedure];
[Social Behavior|Social Behavior];
[Temporal Concept|Cell Function];
[Temporal Concept|Organ or Tissue Function];
[Temporal Concept|Organism Function];
[Temporal Concept|Temporal Concept];
[Tissue|Body System]

UI: T158
RL: conceptually_related_to
ABR: CR
RIN: conceptually_related_to
RTN: R5
DEF: Related by some abstract concept, thought, or idea.
INH: N
HL: {isa} associated_with;
{inverse_isa} property_of;
{inverse_isa} conceptual_part_of;
{inverse_isa} evaluation_of;
{inverse_isa} measures;
{inverse_isa} diagnoses;
{inverse_isa} issue_in;
{inverse_isa} derivative_of;
{inverse_isa} developmental_form_of;
{inverse_isa} degree_of;
{inverse_isa} measurement_of;
{inverse_isa} method_of;
{inverse_isa} analyzes
STL: [Disease or Syndrome|Experimental Model of Disease];
[Individual Behavior|Idea or Concept]

UI: T174
RL: connected_to
ABR: CN
RIN: connected_to
RTN: R1.4
DEF: Directly attached to another physical unit as tendons are connected to
muscles.  This includes attached to and anchored to.
HL: {isa} physically_related_to
STL: [Body Location or Region|Body Location or Region];
[Body Part, Organ, or Organ Component|Body Part, Organ, or Organ Component];
[Body Part, Organ, or Organ Component|Body Space or Junction];
[Body Part, Organ, or Organ Component|Body Substance];
[Body Part, Organ, or Organ Component|Tissue];
[Body Space or Junction|Tissue]

UI: T172
RL: consists_of
ABR: CS
RIN: constitutes
RTN: R1.2
DEF: Is structurally made up of in whole or in part of some material or matter.
This includes composed of, made of, and formed of.
HL: {isa} physically_related_to
STL: [Amino Acid, Peptide, or Protein|Amino Acid, Peptide, or Protein];
[Body Part, Organ, or Organ Component|Body Part, Organ, or Organ Component];
[Body Part, Organ, or Organ Component|Body Substance];
[Body Substance|Body Substance];
[Body Substance|Organic Chemical];
[Cell|Cell];
[Gene or Genome|Gene or Genome];
[Tissue|Tissue]

UI: T134
RL: contains
ABR: CT
RIN: contained_in
RTN: R1.3
DEF: Holds or is the receptacle for fluids or other substances.  This includes is
filled with, holds, and is occupied by.
HL: {isa} physically_related_to
STL: [Body Space or Junction|Body Part, Organ, or Organ Component];
[Body Space or Junction|Body Substance];
[Body Space or Junction|Tissue];
[Drug Delivery Device|Clinical Drug];
[Embryonic Structure|Body Substance];
[Fully Formed Anatomical Structure|Body Substance]

UI: T180
RL: degree_of
ABR: DE
RIN: has_degree
RTN: R5.2
DEF: The relative intensity of a process or the relative intensity or amount of
a quality or attribute.
HL: {isa} conceptually_related_to
STL: [Organ or Tissue Function|Organ or Tissue Function];
[Organism Attribute|Organism Attribute];
[Organism Function|Organism Function];
[Pathologic Function|Pathologic Function];
[Sign or Symptom|Sign or Symptom]

UI: T178
RL: derivative_of
ABR: DO
RIN: has_derivative
RTN: R5.8
DEF: In chemistry, a substance structurally related to another or that can be
made from the other substance.  This is used only for structural relationships.
This does not include functional relationships such as metabolite of, by product
of, nor analog of.
HL: {isa} conceptually_related_to
STL: [Body Substance|Tissue]

UI: T179
RL: developmental_form_of
ABR: DF
RIN: has_developmental_form
RTN: R5.9
DEF: An earlier stage in the individual maturation of.
HL: {isa} conceptually_related_to
STL: [Body Part, Organ, or Organ Component|Body Part, Organ, or Organ Component];
[Cell|Cell];
[Embryonic Structure|Body Part, Organ, or Organ Component];
[Embryonic Structure|Cell];
[Embryonic Structure|Embryonic Structure];
[Embryonic Structure|Tissue];
[Tissue|Body Part, Organ, or Organ Component];
[Tissue|Tissue]

UI: T163
RL: diagnoses
ABR: DI
RIN: diagnosed_by
RTN: R5.6
DEF: Distinguishes or identifies the nature or characteristics of.
HL: {isa} conceptually_related_to
STL: [Diagnostic Procedure|Anatomical Abnormality];
[Diagnostic Procedure|Injury or Poisoning];
[Diagnostic Procedure|Pathologic Function];
[Laboratory Procedure|Anatomical Abnormality];
[Laboratory Procedure|Injury or Poisoning];
[Laboratory Procedure|Pathologic Function];
[Pharmacologic Substance|Pathologic Function];
[Professional or Occupational Group|Pathologic Function];
[Sign or Symptom|Anatomical Abnormality];
[Sign or Symptom|Injury or Poisoning];
[Sign or Symptom|Pathologic Function]

UI: T146
RL: disrupts
ABR: DS
RIN: disrupted_by
RTN: R3.1.3
DEF: Alters or influences an already existing condition, state, or situation.
Produces a negative effect on.
HL: {isa} affects
STL: [Biologically Active Substance|Embryonic Structure];
[Biologically Active Substance|Fully Formed Anatomical Structure];
[Biologically Active Substance|Physiologic Function];
[Hazardous or Poisonous Substance|Embryonic Structure];
[Hazardous or Poisonous Substance|Fully Formed Anatomical Structure];
[Hazardous or Poisonous Substance|Physiologic Function];
[Injury or Poisoning|Embryonic Structure];
[Injury or Poisoning|Fully Formed Anatomical Structure];
[Injury or Poisoning|Physiologic Function];
[Pharmacologic Substance|Embryonic Structure];
[Pharmacologic Substance|Fully Formed Anatomical Structure];
[Pharmacologic Substance|Physiologic Function]

UI: T161
RL: evaluation_of
ABR: EV
RIN: has_evaluation
RTN: R5.1
DEF: Judgment of the value or degree of some attribute or process.
HL: {isa} conceptually_related_to
STL: [Finding|Biologic Function];
[Finding|Organism Attribute];
[Qualitative Concept|Activity]

UI: T145
RL: exhibits
ABR: EX
RIN: exhibited_by
RTN: R3.3.2
DEF: Shows or demonstrates.
HL: {isa} performs
STL: [Animal|Behavior];
[Group|Behavior]

UI: T139
RL: functionally_related_to
ABR: FR
RIN: functionally_related_to
RTN: R3
DEF: Related by the carrying out of some function or activity.
HL: {isa} associated_with;
{inverse_isa} manifestation_of;
{inverse_isa} affects;
{inverse_isa} occurs_in;
{inverse_isa} uses;
{inverse_isa} indicates;
{inverse_isa} result_of;
{inverse_isa} brings_about;
{inverse_isa} performs
STL: <none>

UI: T156
RL: indicates
ABR: IN
RIN: indicated_by
RTN: R3.7
DEF: Gives evidence for the presence at some time of an entity or process.
HL: {isa} functionally_related_to
STL: [Immunologic Factor|Bacterium];
[Immunologic Factor|Pathologic Function];
[Immunologic Factor|Virus];
[Laboratory or Test Result|Anatomical Abnormality];
[Laboratory or Test Result|Biologic Function];
[Laboratory or Test Result|Injury or Poisoning]

UI: T202
RL: ingredient_of
ABR: IG
RIN: has_ingredient
RTN: R1.8
DEF: Is a component of, as in a constituent of a preparation.
HL: {isa} physically_related_to
STL: [Substance|Clinical Drug]

UI: T142
RL: interacts_with
ABR: IW
RIN: interacts_with
RTN: R3.1.5
DEF: Acts, functions, or operates together with.
HL: {isa} affects
STL: [Chemical|Chemical];
[Group|Group];
[Organism|Organism]

UI: T175
RL: interconnects
ABR: IC
RIN: interconnected_by
RTN: R1.5
DEF: Serves to link or join together two or more other physical units.  This
includes joins, links, conjoins, articulates, separates, and bridges.
HL: {isa} physically_related_to
STL: [Body Part, Organ, or Organ Component|Body Space or Junction];
[Body Space or Junction|Cell];
[Embryonic Structure|Embryonic Structure]

UI: T186
RL: isa
ABR: IS
RIN: inverse_isa
RTN: H
DEF: The basic hierarchical link in the Network.  If one item "isa" another item
then the first item is more specific in meaning than the second item.
HL: <none>

UI: T165
RL: issue_in
ABR: II
RIN: has_issue
RTN: R5.12
DEF: Is an issue in or a point of discussion, study, debate, or dispute.
HL: {isa} conceptually_related_to
STL: [Entity|Occupation or Discipline];
[Event|Occupation or Discipline]

UI: T135
RL: location_of
ABR: LO
RIN: has_location
RTN: R2.1
DEF: The position, site, or region of an entity or the site of a process.
HL: {isa} spatially_related_to
STL: [Anatomical Abnormality|Pathologic Function];
[Anatomical Structure|Bacterium];
[Anatomical Structure|Fungus];
[Anatomical Structure|Virus];
[Bacterium|Biologically Active Substance];
[Body Location or Region|Anatomical Abnormality];
[Body Location or Region|Biologic Function];
[Body Location or Region|Body Location or Region];
[Body Location or Region|Body Part, Organ, or Organ Component];
[Body Location or Region|Diagnostic Procedure];
[Body Location or Region|Injury or Poisoning];
[Body Location or Region|Therapeutic or Preventive Procedure];
[Body Location or Region|Tissue];
[Body Part, Organ, or Organ Component|Body Location or Region];
[Body Part, Organ, or Organ Component|Body Space or Junction];
[Body Part, Organ, or Organ Component|Diagnostic Procedure];
[Body Part, Organ, or Organ Component|Therapeutic or Preventive Procedure];
[Body Space or Junction|Anatomical Abnormality];
[Body Space or Junction|Biologic Function];
[Body Space or Junction|Body Space or Junction];
[Body Space or Junction|Body Substance];
[Body Space or Junction|Cell Component];
[Body Space or Junction|Diagnostic Procedure];
[Body Space or Junction|Injury or Poisoning];
[Body Space or Junction|Therapeutic or Preventive Procedure];
[Cell Component|Body Space or Junction];
[Cell Component|Diagnostic Procedure];
[Cell Component|Therapeutic or Preventive Procedure];
[Cell|Body Space or Junction];
[Cell|Diagnostic Procedure];
[Cell|Therapeutic or Preventive Procedure];
[Embryonic Structure|Biologic Function];
[Fully Formed Anatomical Structure|Anatomical Abnormality];
[Fully Formed Anatomical Structure|Biologic Function];
[Fully Formed Anatomical Structure|Injury or Poisoning];
[Fungus|Biologically Active Substance];
[Organization|Occupational Activity];
[Plant|Biologically Active Substance];
[Tissue|Body Space or Junction];
[Tissue|Diagnostic Procedure];
[Tissue|Therapeutic or Preventive Procedure];
[Virus|Biologically Active Substance]

UI: T153
RL: manages
ABR: MN
RIN: managed_by
RTN: R3.1.1
DEF: Administers, or contributes to the care of an individual or group of
individuals.
HL: {isa} affects
STL: [Health Care Related Organization|Patient or Disabled Group];
[Professional or Occupational Group|Organization];
[Self-help or Relief Organization|Patient or Disabled Group]

UI: T150
RL: manifestation_of
ABR: MF
RIN: has_manifestation
RTN: R3.6
DEF: That part of a phenomenon which is directly observable or concretely or
visibly expressed, or which gives evidence to the underlying process.  This
includes expression of, display of, and exhibition of.
HL: {isa} functionally_related_to
STL: [Anatomical Abnormality|Biologic Function];
[Behavior|Mental or Behavioral Dysfunction];
[Behavior|Mental Process];
[Finding|Anatomical Abnormality];
[Finding|Biologic Function];
[Finding|Injury or Poisoning];
[Organism Attribute|Physiologic Function];
[Pathologic Function|Injury or Poisoning];
[Pathologic Function|Pathologic Function];
[Pathologic Function|Physiologic Function]

UI: T182
RL: measurement_of
ABR: ME
RIN: has_measurement
RTN: R5.4
DEF: The dimension, quantity, or capacity determined by measuring.
HL: {isa} conceptually_related_to
STL: [Laboratory or Test Result|Physiologic Function];
[Laboratory or Test Result|Substance];
[Organism Attribute|Physiologic Function];
[Quantitative Concept|Physiologic Function];
[Quantitative Concept|Spatial Concept]

UI: T162
RL: measures
ABR: MS
RIN: measured_by
RTN: R5.5
DEF: Ascertains or marks the dimensions, quantity, degree, or capacity of.
HL: {isa} conceptually_related_to
STL: [Diagnostic Procedure|Body Substance];
[Diagnostic Procedure|Chemical];
[Diagnostic Procedure|Natural Phenomenon or Process];
[Diagnostic Procedure|Organism Attribute];
[Diagnostic Procedure|Quantitative Concept];
[Diagnostic Procedure|Temporal Concept];
[Laboratory Procedure|Body Substance];
[Laboratory Procedure|Chemical];
[Laboratory Procedure|Natural Phenomenon or Process];
[Laboratory Procedure|Organism Attribute];
[Laboratory Procedure|Quantitative Concept];
[Laboratory Procedure|Temporal Concept];
[Research Activity|Body Substance];
[Research Activity|Chemical];
[Research Activity|Natural Phenomenon or Process];
[Research Activity|Organism Attribute];
[Research Activity|Quantitative Concept];
[Research Activity|Temporal Concept]

UI: T183
RL: method_of
ABR: MT
RIN: has_method
RTN: R5.10
DEF: The manner and sequence of events in performing an act or procedure.
HL: {isa} conceptually_related_to
STL: [Diagnostic Procedure|Diagnostic Procedure];
[Laboratory Procedure|Diagnostic Procedure];
[Laboratory Procedure|Laboratory Procedure];
[Laboratory Procedure|Therapeutic or Preventive Procedure];
[Machine Activity|Diagnostic Procedure];
[Machine Activity|Laboratory Procedure];
[Machine Activity|Therapeutic or Preventive Procedure];
[Molecular Biology Research Technique|Diagnostic Procedure];
[Molecular Biology Research Technique|Therapeutic or Preventive Procedure];
[Occupational Activity|Occupation or Discipline];
[Therapeutic or Preventive Procedure|Therapeutic or Preventive Procedure]

UI: T152
RL: occurs_in
ABR: OC
RIN: has_occurrence
RTN: R3.4
DEF: Takes place in or happens under given conditions, circumstances, or time
periods, or in a given location or population.  This includes appears in,
transpires, comes about, is present in, and exists in.
HL: {isa} functionally_related_to;
{inverse_isa} process_of
STL: [Anatomical Abnormality|Group];
[Injury or Poisoning|Group];
[Organ or Tissue Function|Organism Function];
[Pathologic Function|Disease or Syndrome];
[Pathologic Function|Group];
[Pathologic Function|Injury or Poisoning];
[Physiologic Function|Temporal Concept]

UI: T133
RL: part_of
ABR: PT
RIN: has_part
RTN: R1.1
DEF: Composes, with one or more other physical units, some larger whole.  This
includes component of, division of, portion of, fragment of, section of, and
layer of.
HL: {isa} physically_related_to
STL: [Anatomical Structure|Organism];
[Body Part, Organ, or Organ Component|Body Part, Organ, or Organ Component];
[Body Space or Junction|Body Part, Organ, or Organ Component];
[Body Substance|Body Part, Organ, or Organ Component];
[Body Substance|Body Substance];
[Cell Component|Body Part, Organ, or Organ Component];
[Cell Component|Cell Component];
[Cell Component|Cell];
[Cell Component|Tissue];
[Cell|Body Part, Organ, or Organ Component];
[Cell|Cell];
[Cell|Tissue];
[Embryonic Structure|Cell];
[Embryonic Structure|Embryonic Structure];
[Gene or Genome|Body Part, Organ, or Organ Component];
[Gene or Genome|Cell Component];
[Gene or Genome|Cell];
[Gene or Genome|Tissue];
[Nucleotide Sequence|Nucleotide Sequence];
[Tissue|Body Part, Organ, or Organ Component];
[Tissue|Tissue]

UI: T188
RL: performs
ABR: PE
RIN: performed_by
RTN: R3.3
DEF: Executes, accomplishes, or achieves an activity.
HL: {isa} functionally_related_to;
{inverse_isa} carries_out;
{inverse_isa} practices;
{inverse_isa} exhibits
STL: [Group|Activity]

UI: T132
RL: physically_related_to
ABR: PR
RIN: physically_related_to
RTN: R1
DEF: Related by virtue of some physical attribute or characteristic.
HL: {isa} associated_with;
{inverse_isa} part_of;
{inverse_isa} contains;
{inverse_isa} consists_of;
{inverse_isa} connected_to;
{inverse_isa} interconnects;
{inverse_isa} branch_of;
{inverse_isa} tributary_of;
{inverse_isa} ingredient_of
STL: <none>

UI: T143
RL: practices
ABR: PA
RIN: practiced_by
RTN: R3.3.3
DEF: Performs habitually or customarily.
HL: {isa} performs
STL: [Professional or Occupational Group|Occupation or Discipline]

UI: T138
RL: precedes
ABR: PC
RIN: follows
RTN: R4.2
DEF: Occurs earlier in time.  This includes antedates, comes before, is in
advance of, predates, and is prior to.
HL: {isa} temporally_related_to
STL: [Diagnostic Procedure|Therapeutic or Preventive Procedure];
[Pathologic Function|Pathologic Function];
[Physiologic Function|Physiologic Function]

UI: T148
RL: prevents
ABR: PV
RIN: prevented_by
RTN: R3.1.6
DEF: Stops, hinders or eliminates an action or condition.
HL: {isa} affects
STL: [Medical Device|Injury or Poisoning];
[Medical Device|Pathologic Function];
[Pharmacologic Substance|Pathologic Function];
[Therapeutic or Preventive Procedure|Pathologic Function]

UI: T140
RL: process_of
ABR: PO
RIN: has_process
RTN: R3.4.1
DEF: Action, function, or state of.
HL: {isa} occurs_in
STL: [Biologic Function|Organism];
[Individual Behavior|Social Behavior];
[Natural Phenomenon or Process|Natural Phenomenon or Process]
STLB: [Mental or Behavioral Dysfunction|Bacterium];
[Mental or Behavioral Dysfunction|Fungus];
[Mental or Behavioral Dysfunction|Plant];
[Mental or Behavioral Dysfunction|Virus];
[Mental Process|Bacterium];
[Mental Process|Fungus];
[Mental Process|Plant];
[Mental Process|Virus]

UI: T144
RL: produces
ABR: PS
RIN: produced_by
RTN: R3.2.1
DEF: Brings forth, generates or creates.  This includes yields, secretes, emits,
biosynthesizes, generates, releases, discharges, and creates.
HL: {isa} brings_about
STL: [Biologic Function|Biologically Active Substance];
[Biologic Function|Body Substance];
[Disease or Syndrome|Tissue];
[Fully Formed Anatomical Structure|Biologically Active Substance];
[Fully Formed Anatomical Structure|Body Substance];
[Fully Formed Anatomical Structure|Organic Chemical];
[Genetic Function|Cell Component];
[Group|Intellectual Product];
[Group|Manufactured Object];
[Organism Function|Age Group];
[Organism Function|Family Group];
[Organization|Intellectual Product]

UI: T159
RL: property_of
ABR: PP
RIN: has_property
RTN: R5.7
DEF: Characteristic of, or quality of.
HL: {isa} conceptually_related_to
STL: [Amino Acid Sequence|Amino Acid, Peptide, or Protein];
[Amino Acid Sequence|Gene or Genome];
[Group Attribute|Group];
[Nucleotide Sequence|Gene or Genome];
[Nucleotide Sequence|Nucleic Acid, Nucleoside, or Nucleotide];
[Organism Attribute|Organism]

UI: T157
RL: result_of
ABR: RO
RIN: has_result
RTN: R3.8
DEF: The condition, product, or state occurring as a consequence, effect, or
conclusion of an activity or process.  This includes product of, effect of,
sequel of, outcome of, culmination of, and completion of.
HL: {isa} functionally_related_to
STL: [Acquired Abnormality|Behavior];
[Anatomical Abnormality|Anatomical Abnormality];
[Anatomical Abnormality|Health Care Activity];
[Anatomical Abnormality|Phenomenon or Process];
[Behavior|Mental Process];
[Idea or Concept|Mental Process];
[Injury or Poisoning|Behavior];
[Injury or Poisoning|Health Care Activity];
[Laboratory or Test Result|Diagnostic Procedure];
[Laboratory or Test Result|Laboratory Procedure];
[Mental Process|Behavior];
[Organism Attribute|Phenomenon or Process];
[Pathologic Function|Behavior];
[Pathologic Function|Health Care Activity];
[Phenomenon or Process|Anatomical Abnormality];
[Phenomenon or Process|Phenomenon or Process]

UI: T189
RL: spatially_related_to
ABR: SP
RIN: spatially_related_to
RTN: R2
DEF: Related by place or region.
HL: {isa} associated_with;
{inverse_isa} location_of;
{inverse_isa} adjacent_to;
{inverse_isa} surrounds;
{inverse_isa} traverses
STL: <none>

UI: T176
RL: surrounds
ABR: SR
RIN: surrounded_by
RTN: R2.3
DEF: Establishes the boundaries for, or defines the limits of another physical
structure.  This includes limits, bounds, confines, encloses, and circumscribes.
HL: {isa} spatially_related_to
STL: [Body Part, Organ, or Organ Component|Body Part, Organ, or Organ Component];
[Body Part, Organ, or Organ Component|Tissue];
[Body Space or Junction|Body Space or Junction];
[Body Space or Junction|Cell];
[Body Substance|Embryonic Structure];
[Cell Component|Cell Component];
[Embryonic Structure|Cell];
[Embryonic Structure|Embryonic Structure];
[Tissue|Body Space or Junction];
[Tissue|Body Substance];
[Tissue|Cell Component];
[Tissue|Cell];
[Tissue|Tissue]

UI: T136
RL: temporally_related_to
ABR: TR
RIN: temporally_related_to
RTN: R4
DEF: Related in time by preceding, co-occuring with, or following.
HL: {isa} associated_with;
{inverse_isa} co-occurs_with;
{inverse_isa} precedes
STL: <none>

UI: T177
RL: traverses
ABR: TV
RIN: traversed_by
RTN: R2.4
DEF: Crosses or extends across another physical structure or area.  This includes
crosses over and crosses through.
HL: {isa} spatially_related_to
STL: [Body Location or Region|Body Location or Region];
[Body Part, Organ, or Organ Component|Body Part, Organ, or Organ Component]

UI: T154
RL: treats
ABR: TS
RIN: treated_by
RTN: R3.1.2
DEF: Applies a remedy with the object of effecting a cure or managing a
condition.
HL: {isa} affects
STL: [Medical Device|Anatomical Abnormality];
[Medical Device|Injury or Poisoning];
[Medical Device|Pathologic Function];
[Medical Device|Sign or Symptom];
[Pharmacologic Substance|Anatomical Abnormality];
[Pharmacologic Substance|Injury or Poisoning];
[Pharmacologic Substance|Pathologic Function];
[Pharmacologic Substance|Sign or Symptom];
[Professional or Occupational Group|Patient or Disabled Group];
[Therapeutic or Preventive Procedure|Anatomical Abnormality];
[Therapeutic or Preventive Procedure|Injury or Poisoning];
[Therapeutic or Preventive Procedure|Pathologic Function];
[Therapeutic or Preventive Procedure|Sign or Symptom]

UI: T199
RL: tributary_of
ABR: TB
RIN: has_tributary
RTN: R1.7
DEF: Merges with.  For example, the confluence of veins.
HL: {isa} physically_related_to
STL: [Body Part, Organ, or Organ Component|Body Part, Organ, or Organ Component]

UI: T155
RL: uses
ABR: US
RIN: used_by
RTN: R3.5
DEF: Employs in the carrying out of some activity.  This includes applies,
utilizes, employs, and avails.
HL: {isa} functionally_related_to
STL: [Diagnostic Procedure|Manufactured Object];
[Diagnostic Procedure|Pharmacologic Substance];
[Group|Intellectual Product];
[Group|Manufactured Object];
[Research Activity|Research Device];
[Therapeutic or Preventive Procedure|Food];
[Therapeutic or Preventive Procedure|Manufactured Object];
[Therapeutic or Preventive Procedure|Pharmacologic Substance]